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Guisen Zhao Selected Research

Ethacrynic Acid (Etacrynic Acid)

12/2012Ethacrynic acid and a derivative enhance apoptosis in arsenic trioxide-treated myeloid leukemia and lymphoma cells: the role of glutathione S-transferase p1-1.
2/2010Novel oxadiazole analogues derived from ethacrynic acid: design, synthesis, and structure-activity relationships in inhibiting the activity of glutathione S-transferase P1-1 and cancer cell proliferation.
8/2007Ethacrynic acid butyl-ester induces apoptosis in leukemia cells through a hydrogen peroxide mediated pathway independent of glutathione S-transferase P1-1 inhibition.

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Guisen Zhao Research Topics

Disease

14Neoplasms (Cancer)
02/2022 - 01/2006
7Prostatic Neoplasms (Prostate Cancer)
01/2021 - 01/2014
5Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
01/2021 - 01/2019
4Leukemia
02/2022 - 04/2007
3Lymphoma (Lymphomas)
02/2022 - 12/2012
2Acquired Immunodeficiency Syndrome (AIDS)
04/2009 - 07/2007
1Carcinogenesis
01/2022
1Neoplasm Metastasis (Metastasis)
01/2022
1Hypoxia (Hypoxemia)
01/2020
1Autoimmune Diseases (Autoimmune Disease)
07/2018
1B-Cell Leukemia (Leukemia, B Cell)
07/2018
1Adenocarcinoma
08/2013
1Carcinoma (Carcinomatosis)
08/2013
1Myeloid Leukemia (Leukemia, Myelocytic)
12/2012
1Acute Promyelocytic Leukemia
12/2012
1B-Cell Lymphoma (Lymphoma, B Cell)
12/2012

Drug/Important Bio-Agent (IBA)

5Androgen Receptors (Androgen Receptor)IBA
01/2021 - 08/2015
4Biological ProductsIBA
01/2021 - 01/2016
4Glutathione Transferase (Glutathione S-Transferase)IBA
12/2012 - 04/2007
3ibrutinibIBA
02/2022 - 01/2020
3Prostate-Specific Antigen (Semenogelase)IBA
04/2016 - 08/2015
3Ethacrynic Acid (Etacrynic Acid)FDA Link
12/2012 - 08/2007
2Tyrosine (L-Tyrosine)FDA Link
01/2022 - 01/2016
2Phosphotransferases (Kinase)IBA
01/2022 - 01/2016
2Agammaglobulinaemia Tyrosine KinaseIBA
01/2021 - 07/2018
2ethacrynic acid butyl esterIBA
12/2012 - 08/2007
2EnzymesIBA
04/2012 - 04/2009
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
01/2022
1indolin-2-oneIBA
01/2022
1pyrrolopyrimidineIBA
01/2021
1Protein Isoforms (Isoforms)IBA
01/2020
1AminesIBA
01/2020
1pyrimidineIBA
09/2017
1ThiohydantoinsIBA
01/2016
1Androgen Antagonists (Antiandrogens)IBA
01/2016
1Transcription Factors (Transcription Factor)IBA
11/2015
1LigandsIBA
11/2015
1Androgen Receptor AntagonistsIBA
11/2015
1AndrogensIBA
11/2015
1enzalutamideIBA
08/2015
1Proteins (Proteins, Gene)FDA Link
01/2014
1anthranilamideIBA
08/2013
1Arsenic Trioxide (Trisenox)FDA Link
12/2012
1Cytochromes c (Cytochrome c)IBA
12/2012
1Therapeutic UsesIBA
12/2012
1Caspase 3 (Caspase-3)IBA
12/2012
1SelenocysteineIBA
10/2012
1Pharmaceutical PreparationsIBA
10/2012
1Glutathione S-Transferase piIBA
04/2012
1OxadiazolesIBA
02/2010
1Human immunodeficiency virus 1 p31 integrase proteinIBA
04/2009
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
08/2007
1DiureticsIBA
08/2007
1IntegrasesIBA
07/2007
1AcidsIBA
07/2007
1O-(glucuronic acid 2-sulfate)-(1--3)-O-(2,5)-andydrotalitol 6-sulfateIBA
01/2006

Therapy/Procedure

9Therapeutics
01/2022 - 04/2009
3Castration
01/2021 - 11/2015
1Drug Therapy (Chemotherapy)
01/2020